KEGG   REACTION: R08808
Entry
R08808                      Reaction                               
Name
feruloyl-CoA:p-coumaroyl-diketide-CoA C-feruloyltransferase (thioester-hydrolysing and decarboxylating)
Definition
p-Coumaroyl-diketide-CoA + Feruloyl-CoA + H2O <=> Demethoxycurcumin + 2 CoA + CO2
Equation
C17740 + C00406 + C00001 <=> C17742 + 2 C00010 + C00011
Comment
curcuminoid synthase (CURS)
Reaction class
RC00004  C00010_C00406  C00010_C17740
RC02970  C17740_C17742
Enzyme
2.3.1.217
Pathway
rn00945  Stilbenoid, diarylheptanoid and gingerol biosynthesis
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.217
     R08808  p-Coumaroyl-diketide-CoA + Feruloyl-CoA + H2O <=> Demethoxycurcumin + 2 CoA + CO2
Orthology
K13234  curcumin synthase [EC:2.3.1.217]
K17211  curcumin/demethoxycurcumin synthase [EC:2.3.1.217 2.3.1.219]
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