REACTION: R08959
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Entry
R08959 Reaction
Name
5alpha-pregnane-3alpha,20alpha-diol:NADP+ 20-oxidoreductase
Definition
5alpha-Pregnane-3alpha,20alpha-diol + NADP+ <=> Allopregnanolone + NADPH + H+
Equation
C18042
+
C00006
<=>
C13712
+
C00005
+
C00080
Reaction class
RC00001
C00005_C00006
RC00139
C13712_C18042
Enzyme
1.1.1.149
Pathway
rn00140
Steroid hormone biosynthesis
rn01100
Metabolic pathways
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.149
R08959 5alpha-Pregnane-3alpha,20alpha-diol + NADP+ <=> Allopregnanolone + NADPH + H+
BRITE hierarchy
Orthology
K00212
20alpha/3alpha-hydroxysteroid dehydrogenase / dihydrodiol dehydrogenase [EC:
1.1.1.149
1.1.1.357
1.3.1.20
]
K05295
20alpha-hydroxysteroid dehydrogenase [EC:
1.1.1.149
]
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