KEGG   REACTION: R08960
Entry
R08960                      Reaction                               
Name
5alpha-pregnane-3alpha,20alpha-diol:NADP+ oxidoreductase (A-specific)
Definition
5alpha-Pregnan-20alpha-ol-3-one + NADPH + H+ <=> 5alpha-Pregnane-3alpha,20alpha-diol + NADP+
Equation
C18041 + C00005 + C00080 <=> C18042 + C00006
Reaction class
RC00001  C00005_C00006
RC00144  C18041_C18042
Enzyme
1.1.1.213
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.213
     R08960  5alpha-Pregnan-20alpha-ol-3-one + NADPH + H+ <=> 5alpha-Pregnane-3alpha,20alpha-diol + NADP+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.1.1.213
   R10423  3alpha-Hydroxysteroid <=> 3-Oxosteroid
    R08960  5alpha-Pregnane-3alpha,20alpha-diol <=> 5alpha-Pregnan-20alpha-ol-3-one
Orthology
K00089  3alpha-hydroxysteroid 3-dehydrogenase [EC:1.1.1.213 1.1.1.357]
K04119  aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
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