KEGG   REACTION: R09313
Entry
R09313                      Reaction                               
Name
dihydrokalafungin-dihydroquinone,FMNH2:oxygen oxidoreductase (hydroxylating)
Definition
Dihydrokalafungin dihydroquinone form + Reduced FMN + Oxygen <=> DHKred-OH + FMN + H2O
Equation
C18360 + C01847 + C00007 <=> C18358 + C00061 + C00001
Reaction class
RC00046  C18358_C18360
RC00126  C00061_C01847
Enzyme
1.14.14.-
Pathway
rn01057  Biosynthesis of type II polyketide products
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.-
     R09313  Dihydrokalafungin dihydroquinone form + Reduced FMN + Oxygen <=> DHKred-OH + FMN + H2O
Orthology
K14630  two-component flavin-dependent monooxygenase [EC:1.14.14.-]
Reference
1  [PMID:18245777]
  Authors
Valton J, Mathevon C, Fontecave M, Niviere V, Ballou DP
  Title
Mechanism and regulation of the Two-component FMN-dependent monooxygenase ActVA-ActVB from Streptomyces coelicolor.
  Journal
J Biol Chem 283:10287-96 (2008)
DOI:10.1074/jbc.M709730200
Reference
2  [PMID:16267053]
  Authors
Valton J, Fontecave M, Douki T, Kendrew SG, Niviere V
  Title
An aromatic hydroxylation reaction catalyzed by a two-component FMN-dependent Monooxygenase. The ActVA-ActVB system from Streptomyces coelicolor.
  Journal
J Biol Chem 281:27-35 (2006)
DOI:10.1074/jbc.M506146200
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