KEGG   REACTION: R09423
Entry
R09423                      Reaction                               
Definition
4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone + Oxygen + NADPH + H+ <=> 4-Hydroxy-4-(methylnitrosoamino)-1-(3-pyridinyl)-1-butanone + H2O + NADP+
Equation
C16453 + C00007 + C00005 + C00080 <=> C19566 + C00001 + C00006
Comment
CYP2A6, CYP2A13, CYP1A1, CYP3A4
Reaction class
RC00001  C00005_C00006
RC02531  C16453_C19566
Enzyme
1.14.14.1       1.14.14.-
Pathway
rn00980  Metabolism of xenobiotics by cytochrome P450
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1
     R09423  4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone + Oxygen + NADPH + H+ <=> 4-Hydroxy-4-(methylnitrosoamino)-1-(3-pyridinyl)-1-butanone + H2O + NADP+
    1.14.14.-
     R09423  4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone + Oxygen + NADPH + H+ <=> 4-Hydroxy-4-(methylnitrosoamino)-1-(3-pyridinyl)-1-butanone + H2O + NADP+
Orthology
K07408  cytochrome P450 family 1 subfamily A1 [EC:1.14.14.1]
K17683  cytochrome P450 family 2 subfamily A6 [EC:1.14.14.-]
K17685  cytochrome P450 family 2 subfamily A13 [EC:1.14.14.1]
K17689  cytochrome P450 family 3 subfamily A4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.14.-]
LinkDB

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