KEGG   REACTION: R09827
Entry
R09827                      Reaction                               
Name
1-phosphatidyl-1D-myo-inositol-3,4,5-trisphosphate 5-phosphohydrolase
Definition
Phosphatidylinositol-3,4,5-trisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate + Orthophosphate
Equation
C05981 + C00001 <=> C11554 + C00009
Reaction class
RC00078  C05981_C11554
Enzyme
3.1.3.36        3.1.3.86
Pathway
rn00562  Inositol phosphate metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.36
     R09827  Phosphatidylinositol-3,4,5-trisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate + Orthophosphate
    3.1.3.86
     R09827  Phosphatidylinositol-3,4,5-trisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate + Orthophosphate
Orthology
K01099  inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
K03084  phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86]
K15909  phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
K20278  inositol polyphosphate 5-phosphatase INPP5E [EC:3.1.3.36]
K20279  synaptojanin [EC:3.1.3.36]
Other DBs
RHEA: 25531
LinkDB

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