KEGG   REACTION: R09920
Entry
R09920                      Reaction                               
Name
cholesterol:NAD+ 3-oxidoreductase;
cholest-4-en-3-one delta5-delat4-isomerase
Definition
Cholesterol + NAD+ <=> Cholest-4-en-3-one + NADH + H+
Equation
Comment
multi-step reaction (see R03176+R02644)
Reaction class
RC00001  C00003_C00004
RC00146  C00187_C00599
Enzyme
1.1.1.145       5.3.3.1
Pathway
rn00984  Steroid degradation
rn01120  Microbial metabolism in diverse environments
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.145
     R09920  Cholesterol + NAD+ <=> Cholest-4-en-3-one + NADH + H+
 5. Isomerase reactions
  5.3  Intramolecular oxidoreductases
   5.3.3  Transposing C=C bonds
    5.3.3.1
     R09920  Cholesterol + NAD+ <=> Cholest-4-en-3-one + NADH + H+
Orthology
K16045  3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
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