KEGG   REACTION: R10243
Entry
R10243                      Reaction                               
Definition
Tetrahydrofolate + Acetyl-CoA <=> 5-Methyltetrahydrofolate + CoA + CO
Equation
Comment
two-step reaction (see R08433+R02289)
Reaction class
RC00004  C00010_C00024
RC00113  C00101_C00440
RC02963  C00024_C00237
RC02977  C00024_C00440
Enzyme
2.1.1.258       2.3.1.169
Pathway
rn00720  Carbon fixation pathways in prokaryotes
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Module
M00377  Reductive acetyl-CoA pathway (Wood-Ljungdahl pathway)
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.258
     R10243  Tetrahydrofolate + Acetyl-CoA <=> 5-Methyltetrahydrofolate + CoA + CO
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.169
     R10243  Tetrahydrofolate + Acetyl-CoA <=> 5-Methyltetrahydrofolate + CoA + CO
Overall reaction [br08210.html]
 Carbon fixation
  R10243
Orthology
K00194  acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245]
K00197  acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245]
K14138  acetyl-CoA synthase [EC:2.3.1.169]
K15023  5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase [EC:2.1.1.258]
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