KEGG   REACTION: R10396
Entry
R10396                      Reaction                               
Name
(-)-threo-iso(homo)3-citrate hydro-lyase
Definition
cis-(Homo)3-aconitate + H2O <=> (-)-threo-Iso(homo)3-citrate
Equation
Comment
second step of two-step reaction (see R10394, R10395+R10396)
Reaction class
RC00618  C16600_C20582
Enzyme
Pathway
rn00680  Methane metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01210  2-Oxocarboxylic acid metabolism
Module
M00608  2-Oxocarboxylic acid chain extension, 2-oxoglutarate => 2-oxoadipate => 2-oxopimelate => 2-oxosuberate
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.114
     R10396  cis-(Homo)3-aconitate + H2O <=> (-)-threo-Iso(homo)3-citrate
Orthology
K16792  methanogen homoaconitase large subunit [EC:4.2.1.114]
K16793  methanogen homoaconitase small subunit [EC:4.2.1.114]
Reference
1  [PMID:10940051]
  Authors
Howell DM, Graupner M, Xu H, White RH
  Title
Identification of enzymes homologous to isocitrate dehydrogenase that are involved in coenzyme B and leucine biosynthesis in methanoarchaea.
  Journal
J Bacteriol 182:5013-6 (2000)
DOI:10.1128/JB.182.17.5013-5016.2000
Other DBs
RHEA: 68423
LinkDB

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