REACTION: R10826
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Entry
R10826 Reaction
Name
very-long-chain-(3R)-3-hydroxyacyl-CoA:NADP+ oxidoreductase
Definition
Very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+ <=> Very-long-chain 3-oxoacyl-CoA + NADPH + H+
Equation
C20878
+
C00006
<=>
C20877
+
C00005
+
C00080
Comment
Elongation of C16/C18 acyl-CoAs to very-long-chain acyl CoAs.
Reaction class
RC00001
C00005_C00006
RC00103
C20877_C20878
Enzyme
1.1.1.330
Pathway
rn00062
Fatty acid elongation
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.330
R10826 Very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+ <=> Very-long-chain 3-oxoacyl-CoA + NADPH + H+
BRITE hierarchy
Orthology
K10251
17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:
1.1.1.62
1.1.1.330
]
Other DBs
RHEA:
48683
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