KEGG   REACTION: R11121
Entry
R11121                      Reaction                               
Definition
Chromopyrrolate + 2 Oxygen + 2 NADH + 3 H+ <=> K-252c + 2 CO2 + 3 H2O + 2 NAD+
Equation
C21125 + 2 C00007 + 2 C00004 + 3 C00080 <=> C21126 + 2 C00011 + 3 C00001 + 2 C00003
Reaction class
RC00001  C00003_C00004
RC03361  C21125_C21126
Enzyme
1.13.12.-
Pathway
rn00404  Staurosporine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00805  Staurosporine biosynthesis, tryptophan => staurosporine
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.12  With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
    1.13.12.-
     R11121  Chromopyrrolate + 2 Oxygen + 2 NADH + 3 H+ <=> K-252c + 2 CO2 + 3 H2O + 2 NAD+
Orthology
K20077  flavin-dependent monooxygenase StaC [EC:1.13.12.-]
K20078  cytochrome P450 StaP [EC:1.13.12.-]
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