KEGG   REACTION: R11142
Entry
R11142                      Reaction                               
Name
5beta-cholestane-3alpha,7alpha,12alpha-triol,adrenodoxin:oxygen oxidoreductase (26-hydroxylating)
Definition
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane + 6 Reduced adrenal ferredoxin + 6 H+ + 3 Oxygen <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate + 6 Oxidized adrenal ferredoxin + 4 H2O
Equation
C05454 + 6 C00662 + 6 C00080 + 3 C00007 <=> C04722 + 6 C00667 + 4 C00001
Comment
three-step reaction (see R04807+R03507+R08761)
Reaction class
RC03368  C04722_C05454
Enzyme
1.14.15.15
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.15
     R11142  3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane + 6 Reduced adrenal ferredoxin + 6 H+ + 3 Oxygen <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate + 6 Oxidized adrenal ferredoxin + 4 H2O
Orthology
K00488  cholestanetriol 26-monooxygenase [EC:1.14.15.15]
Other DBs
RHEA: 34634
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