KEGG   REACTION: R11282
Entry
R11282                      Reaction                               
Name
UDP-N-acetyl-alpha-D-glucosamine:5-ribosylparomamine N-acetyl-D-glucosaminyltransferase
Definition
UDP-N-acetyl-alpha-D-glucosamine + 5-Ribosylparomamine <=> UDP + 2'''-N-Acetyl-6'''-deamino-6'''-hydroxyparomomycin II
Equation
Comment
deduced reaction
Reaction class
RC00005  C00015_C00043
RC00049  C18002_C21261
Enzyme
2.4.1.-
Pathway
rn00524  Neomycin, kanamycin and gentamicin biosynthesis
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.-
     R11282  UDP-N-acetyl-alpha-D-glucosamine + 5-Ribosylparomamine <=> UDP + 2'''-N-Acetyl-6'''-deamino-6'''-hydroxyparomomycin II
Orthology
K20582  N-acetylglucosaminyltransferase [EC:2.4.1.-]
Reference
1  [PMID:21689223]
  Authors
Clausnitzer D, Piepersberg W, Wehmeier UF
  Title
The oxidoreductases LivQ and NeoQ are responsible for the different 6'-modifications in the aminoglycosides lividomycin and neomycin.
  Journal
J Appl Microbiol 111:642-51 (2011)
DOI:10.1111/j.1365-2672.2011.05082.x
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