KEGG   REACTION: R11478
Entry
R11478                      Reaction                               
Name
tetracycline:FADH2 oxidoreductase (7-halogenating)
Definition
Tetracycline + FADH2 + Cl- + Oxygen + H+ <=> Chlortetracycline + FAD + 2 H2O
Equation
C06570 + C01352 + C00698 + C00007 + C00080 <=> C06571 + C00016 + 2 C00001
Reaction class
RC00949  C06570_C06571
Enzyme
1.14.19.49
Pathway
rn00253  Tetracycline biosynthesis
rn01057  Biosynthesis of type II polyketide products
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00823  Chlortetracycline biosynthesis, pretetramide => chlortetracycline
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.49
     R11478  Tetracycline + FADH2 + Cl- + Oxygen + H+ <=> Chlortetracycline + FAD + 2 H2O
Orthology
K14257  tetracycline 7-halogenase / FADH2 O2-dependent halogenase [EC:1.14.19.49 1.14.19.-]
Other DBs
RHEA: 50715
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