KEGG   REACTION: R11687
Entry
R11687                      Reaction                               
Name
(S)-N-methylcanadine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (1-hydroxylating)
Definition
(S)-cis-N-Methylcanadine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (S)-1-Hydroxy-cis-N-methylcanadine + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C02915 + C03024 + C00007 <=> C21586 + C03161 + C00001
Comment
N-methylcanadine 1-hydroxylase
Reaction class
RC00236  C02915_C21586
Enzyme
1.14.14.166
Pathway
rn00950  Isoquinoline alkaloid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00946  Noscapine biosynthesis, (S)-reticuline => noscapine
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.166
     R11687  (S)-cis-N-Methylcanadine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> (S)-1-Hydroxy-cis-N-methylcanadine + [Oxidized NADPH---hemoprotein reductase] + H2O
Orthology
K20621  (S)-N-methylcanadine 1-hydroxylase [EC:1.14.14.166]
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