REACTION: R11768
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Entry
R11768 Reaction
Name
2,5-dioxopentanoate:NAD+ 5-oxidoreductase
Definition
2,5-Dioxopentanoate + NAD+ + H2O <=> 2-Oxoglutarate + NADH + H+
Equation
C00433
+
C00003
+
C00001
<=>
C00026
+
C00004
+
C00080
Reaction class
RC00080
C00026_C00433
Enzyme
1.2.1.-
Pathway
rn00040
Pentose and glucuronate interconversions
rn01100
Metabolic pathways
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.-
R11768 2,5-Dioxopentanoate + NAD+ + H2O <=> 2-Oxoglutarate + NADH + H+
BRITE hierarchy
Orthology
K22187
alpha-ketoglutaric semialdehyde dehydrogenase [EC:1.2.1.-]
Other DBs
RHEA:
47155
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