KEGG   REACTION: R12002
Entry
R12002                      Reaction                               
Name
Fe-coproporphyrin III:S-adenosyl-L-methionine oxidoreductase (decarboxylating)
Definition
Fe-coproporphyrin III + 2 S-Adenosyl-L-methionine <=> Heme + 2 CO2 + 2 5'-Deoxyadenosine + 2 L-Methionine
Equation
C21284 + 2 C00019 <=> C00032 + 2 C00011 + 2 C05198 + 2 C00073
Reaction class
RC00884  C00032_C21284
Enzyme
Pathway
rn00860  Porphyrin metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01240  Biosynthesis of cofactors
Module
M00847  Heme biosynthesis, archaea, siroheme => heme
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.3  Acting on the CH-CH group of donors
   1.3.98  With other, known, physiological acceptors
    1.3.98.6
     R12002  Fe-coproporphyrin III + 2 S-Adenosyl-L-methionine <=> Heme + 2 CO2 + 2 5'-Deoxyadenosine + 2 L-Methionine
Orthology
K22227  AdoMet-dependent heme synthase [EC:1.3.98.6]
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