Entry
Definition
Anthraniloyl-CoA + 2 Malonyl-CoA <=> 2-Methylquinolin-4-ol + 3 CO2 + 3 CoA
Equation
Enzyme
2.3.1.-
Pathway
rn00998 Biosynthesis of various antibiotics
rn01110 Biosynthesis of secondary metabolites
Module
M00848 Aurachin biosynthesis, anthranilate => aurachin A
Brite
Enzymatic reactions [BR:br08201 ]
2. Transferase reactions
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.-
R12049 Anthraniloyl-CoA + 2 Malonyl-CoA <=> 2-Methylquinolin-4-ol + 3 CO2 + 3 CoA
BRITE hierarchy
Orthology
K14245 PKS ketosynthase (KS/KS alpha) [EC:2.3.1.-]
K14246 PKS chain-length factor (CLF/KS beta) [EC:2.3.1.-]
K22798 anthranilate-CoA-ACP transferase [EC:6.2.1.-]
Reference
Authors
Sandmann A, Dickschat J, Jenke-Kodama H, Kunze B, Dittmann E, Muller R
Title
A Type II polyketide synthase from the gram-negative Bacterium Stigmatella aurantiaca is involved in Aurachin alkaloid biosynthesis.
Journal
LinkDB
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