KEGG   REACTION: R12355
Entry
R12355                      Reaction                               
Definition
Squalene + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (S)-2,3-Epoxysqualene + 2 Ferricytochrome b5 + H2O
Equation
C00751 + 2 C00999 + C00007 + 2 C00080 <=> C01054 + 2 C00996 + C00001
Comment
squalene,ferrocytochrome-b5:oxygen oxidoreductase
Reaction class
RC00201  C00751_C01054
Enzyme
1.14.19.-
Pathway
rn00100  Steroid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.-
     R12355  Squalene + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> (S)-2,3-Epoxysqualene + 2 Ferricytochrome b5 + H2O
Orthology
K23485  alternative squalene epoxidase [EC:1.14.19.-]
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