KEGG   REACTION: R12377
Entry
R12377                      Reaction                               
Name
24-methylidenecycloartanol,ferrocytochrome-b5:oxygen oxidoreductase (C-4alpha-methyl-hydroxylating)
Definition
24-Methylidenecycloartanol + 6 Ferrocytochrome b5 + 3 Oxygen + 6 H+ <=> 3beta-Hydroxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-4alpha-carboxylate + 6 Ferricytochrome b5 + 4 H2O
Equation
C08830 + 6 C00999 + 3 C00007 + 6 C00080 <=> C22116 + 6 C00996 + 4 C00001
Comment
three-step reaction (see R12368+R12369+R12370)
Reaction class
RC01952  C08830_C22116
Enzyme
1.14.18.10
Pathway
rn00100  Steroid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00917  Phytosterol biosynthesis, squalene 2,3-epoxide => campesterol/sitosterol
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.18  With another compound as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.18.10
     R12377  24-Methylidenecycloartanol + 6 Ferrocytochrome b5 + 3 Oxygen + 6 H+ <=> 3beta-Hydroxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-4alpha-carboxylate + 6 Ferricytochrome b5 + 4 H2O
Orthology
K14423  plant 4,4-dimethylsterol C-4alpha-methyl-monooxygenase [EC:1.14.18.10]
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