REACTION: R12488
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Entry
R12488 Reaction
Name
(R)-3-(aryl)lactoyl-CoA hydro-lyase
Definition
(R)-3-(4-Hydroxyphenyl)lactoyl-CoA <=> p-Coumaroyl-CoA + H2O
Equation
C22205
<=>
C00223
+
C00001
Enzyme
4.2.1.175
Brite
Enzymatic reactions [BR:
br08201
]
4. Lyase reactions
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.175
R12488 (R)-3-(4-Hydroxyphenyl)lactoyl-CoA <=> p-Coumaroyl-CoA + H2O
BRITE hierarchy
Reference
1 [PMID:
29168502
]
Authors
Dodd D, Spitzer MH, Van Treuren W, Merrill BD, Hryckowian AJ, Higginbottom SK, Le A, Cowan TM, Nolan GP, Fischbach MA, Sonnenburg JL
Title
A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites.
Journal
Nature 551:648-652 (2017)
DOI:
10.1038/nature24661
Other DBs
RHEA:
60111
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