KEGG   REACTION: R12596
Entry
R12596                      Reaction                               
Definition
Spermidine + Citrate + ATP <=> N-Citryl-spermidine + AMP + Diphosphate
Equation
Enzyme
6.3.2.-
Pathway
rn01053  Biosynthesis of siderophore group nonribosomal peptides
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.-
     R12596  Spermidine + Citrate + ATP <=> N-Citryl-spermidine + AMP + Diphosphate
Orthology
K24108  spermidine-citrate ligase [EC:6.3.2.-]
Reference
1  [PMID:17579415]
  Authors
Oves-Costales D, Kadi N, Fogg MJ, Song L, Wilson KS, Challis GL
  Title
Enzymatic logic of anthrax stealth siderophore biosynthesis: AsbA catalyzes ATP-dependent condensation of citric acid and spermidine.
  Journal
J Am Chem Soc 129:8416-7 (2007)
DOI:10.1021/ja072391o
Reference
2  [PMID:18758617]
  Authors
Oves-Costales D, Kadi N, Fogg MJ, Song L, Wilson KS, Challis GL
  Title
Petrobactin biosynthesis: AsbB catalyzes condensation of spermidine with N8-citryl-spermidine and its N1-(3,4-dihydroxybenzoyl) derivative.
  Journal
Chem Commun (Camb) 4034-6 (2008)
DOI:10.1039/b809353a
Other DBs
RHEA: 63811
LinkDB

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