KEGG   REACTION: R12659
Entry
R12659                      Reaction                               
Definition
Tryptamine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Serotonin + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
Comment
tryptamine 5-hydroxylase
Reaction class
RC00490  C00398_C00780
Enzyme
1.14.-.-
Pathway
rn00380  Tryptophan metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00936  Melatonin biosynthesis, plants, tryptophan => serotonin => melatonin
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.-  Acting on paired donors, with incorporation or reduction of molecular oxygen
    1.14.-.-
     R12659  Tryptamine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Serotonin + [Oxidized NADPH---hemoprotein reductase] + H2O
Orthology
K24541  tryptamine 5-hydroxylase [EC:1.14.-.-]
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