KEGG   REACTION: R12847
Entry
R12847                      Reaction                               
Definition
22-Hydroxycholesterol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 22,26-Dihydroxycholesterol + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C22446 + C03024 + C00007 <=> C22447 + C03161 + C00001
Comment
C26-hydroxylase
Reaction class
RC01216  C22446_C22447
Enzyme
1.14.14.-
Pathway
rn00996  Biosynthesis of various alkaloids
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.-
     R12847  22-Hydroxycholesterol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 22,26-Dihydroxycholesterol + [Oxidized NADPH---hemoprotein reductase] + H2O
Orthology
K25490  22-hydroxycholesterol 26-hydroxylase [EC:1.14.14.-]
LinkDB

DBGET integrated database retrieval system