KEGG   REACTION: R13031
Entry
R13031                      Reaction                               
Definition
L-Tyrosine + NADPH + Oxygen + H+ <=> 3,4-Dihydroxy-L-phenylalanine + NADP+ + H2O
Equation
Comment
tyrosine hydroxylase
Reaction class
RC00046  C00082_C00355
Enzyme
1.14.-.-
Pathway
rn00965  Betalain biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00961  Betacyanin biosynthesis, L-tyrosine => amaranthin
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.-  Acting on paired donors, with incorporation or reduction of molecular oxygen
    1.14.-.-
     R13031  L-Tyrosine + NADPH + Oxygen + H+ <=> 3,4-Dihydroxy-L-phenylalanine + NADP+ + H2O
Orthology
K26037  tyrosine hydroxylase / L-DOPA oxygenase [EC:1.14.-.-]
Reference
1  [PMID:32745157]
  Authors
Lichman BR.
  Title
The scaffold-forming steps of plant alkaloid biosynthesis.
  Journal
Nat Prod Rep 38:103-129 (2021)
DOI:10.1039/d0np00031k
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