REACTION: R13038
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Entry
R13038 Reaction
Name
(3R)-3-[(carboxylmethyl)amino]fatty acid glycine-lyase ((2E)-unsaturated fatty acyl-[acyl-carrier protein]-forming)
Definition
(3R)-3-[(Carboxylmethyl)amino]fatty acid + Acyl-carrier protein <=> trans-2,3-Dehydroacyl-[acyl-carrier protein] + Glycine + H2O
Equation
C22516
+
C00229
<=>
C00693
+
C00037
+
C00001
Enzyme
4.3.2.11
Brite
Enzymatic reactions [BR:
br08201
]
4. Lyase reactions
4.3 Carbon-nitrogen lyases
4.3.2 Amidine-lyases
4.3.2.11
R13038 (3R)-3-[(Carboxylmethyl)amino]fatty acid + Acyl-carrier protein <=> trans-2,3-Dehydroacyl-[acyl-carrier protein] + Glycine + H2O
BRITE hierarchy
Orthology
K26055
(3R)-3-[(carboxylmethyl)amino]fatty acid synthase [EC:
4.3.2.11
]
Reference
1 [PMID:
28634299
]
Authors
Harris NC, Sato M, Herman NA, Twigg F, Cai W, Liu J, Zhu X, Downey J, Khalaf R, Martin J, Koshino H, Zhang W.
Title
Biosynthesis of isonitrile lipopeptides by conserved nonribosomal peptide synthetase gene clusters in Actinobacteria.
Journal
Proc Natl Acad Sci U S A 114:7025-7030 (2017)
DOI:
10.1073/pnas.1705016114
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