REACTION: R13040
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Entry
R13040 Reaction
Definition
5(S)-HETE + NADP+ <=> 5-OxoETE + NADPH + H+
Equation
C04805
+
C00006
<=>
C14732
+
C00005
+
C00080
Comment
5-hydroxyeicosanoid dehydrogenase
Reaction class
RC00241
C04805_C14732
Enzyme
1.1.1.-
Pathway
rn00590
Arachidonic acid metabolism
rn01100
Metabolic pathways
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.-
R13040 5(S)-HETE + NADP+ <=> 5-OxoETE + NADPH + H+
BRITE hierarchy
Reference
1 [PMID:
24056189
]
Authors
Powell WS, Rokach J.
Title
The eosinophil chemoattractant 5-oxo-ETE and the OXE receptor.
Journal
Prog Lipid Res 52:651-65 (2013)
DOI:
10.1016/j.plipres.2013.09.001
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