KEGG   REACTION: R13054
Entry
R13054                      Reaction                               
Definition
Daidzein + NADPH + H+ <=> (R)-Dihydrodaidzein + NADP+
Equation
C10208 + C00005 + C00080 <=> C22556 + C00006
Comment
daidzein reductase
Reaction class
RC00805  C10208_C22556
Enzyme
1.3.1.-
Pathway
rn00946  Degradation of flavonoids
rn01100  Metabolic pathways
Module
M00966  Equol biosynthesis, daidzein => equol
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.-
     R13054  Daidzein + NADPH + H+ <=> (R)-Dihydrodaidzein + NADP+
Orthology
K26069  daidzein reductase [EC:1.3.1.-]
Reference
1  [PMID:27508112]
  Authors
Kawada Y, Yokoyama S, Yanase E, Niwa T, Suzuki T
  Title
The production of S-equol from daidzein is associated with a cluster of three genes in Eggerthella sp. YY7918.
  Journal
Biosci Microbiota Food Health 35:113-21 (2016)
DOI:10.12938/bmfh.2015-023
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