REACTION: R13056
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Entry
R13056 Reaction
Definition
(S)-Dihydrodaidzein + NADPH + H+ <=> (3S,4R)-Tetrahydrodaidzein + NADP+
Equation
C22557
+
C00005
+
C00080
<=>
C22558
+
C00006
Comment
dihydrodaidzein reductase
Reaction class
RC00235
C22557_C22558
Enzyme
1.1.1.-
Pathway
rn00946
Degradation of flavonoids
rn01100
Metabolic pathways
Module
M00966
Equol biosynthesis, daidzein => equol
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.-
R13056 (S)-Dihydrodaidzein + NADPH + H+ <=> (3S,4R)-Tetrahydrodaidzein + NADP+
BRITE hierarchy
Orthology
K26070
dihydrodaidzein reductase [EC:1.1.1.-]
Reference
1 [PMID:
27508112
]
Authors
Kawada Y, Yokoyama S, Yanase E, Niwa T, Suzuki T
Title
The production of S-equol from daidzein is associated with a cluster of three genes in Eggerthella sp. YY7918.
Journal
Biosci Microbiota Food Health 35:113-21 (2016)
DOI:
10.12938/bmfh.2015-023
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