REACTION: R13148
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Entry
R13148 Reaction
Definition
L-Glutamate 5-semialdehyde + NADP+ + H2O <=> L-Glutamate + NADPH + H+
Equation
C01165
+
C00006
+
C00001
<=>
C00025
+
C00005
+
C00080
Comment
the second step of two-step reaction (see
R00708, R03314+R13148
)
following after
R03314
Reaction class
RC00080
C00025_C01165
Enzyme
1.2.1.88
Pathway
rn00330
Arginine and proline metabolism
rn01100
Metabolic pathways
Module
M00970
Proline degradation, proline => glutamate
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.88
R13148 L-Glutamate 5-semialdehyde + NADP+ + H2O <=> L-Glutamate + NADPH + H+
BRITE hierarchy
Orthology
K00294
1-pyrroline-5-carboxylate dehydrogenase [EC:
1.2.1.88
]
K13821
RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:
1.5.5.2
1.2.1.88
]
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