KEGG   REACTION: R13213
Entry
R13213                      Reaction                               
Name
allopregnanolone,NADPH---hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating)
Definition
Allopregnanolone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 5alpha-Pregnane-3alpha,17alpha-diol-20-one + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
Reaction class
RC00660  C13712_C22832
Enzyme
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.19
     R13213  Allopregnanolone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 5alpha-Pregnane-3alpha,17alpha-diol-20-one + [Oxidized NADPH---hemoprotein reductase] + H2O
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.14.14.19
   R02131  Steroid <=> 17alpha-Hydroxysteroid
    R13213  Allopregnanolone <=> 5alpha-Pregnane-3alpha,17alpha-diol-20-one
Orthology
K00512  steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
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