KEGG   REACTION: R13271
Entry
R13271                      Reaction                               
Name
ultra-long-chain-di-unsaturated-(3R)-3-hydroxyacyl-[acyl-carrier protein]:NADP+ oxidoreductase
Definition
Ultra-long-chain di-unsaturated (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ <=> Ultra-long-chain di-unsaturated 3-oxo-fatty acyl-[acyl-carrier protein] + NADPH + H+
Equation
C22871 + C00006 <=> C22870 + C00005 + C00080
Comment
general reaction
Enzyme
1.1.1.-
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.-
     R13271  Ultra-long-chain di-unsaturated (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ <=> Ultra-long-chain di-unsaturated 3-oxo-fatty acyl-[acyl-carrier protein] + NADPH + H+
Orthology
K11610  beta-ketoacyl ACP reductase [EC:1.1.1.100]
Reference
1  [PMID:20178986]
  Authors
Veyron-Churlet R, Zanella-Cleon I, Cohen-Gonsaud M, Molle V, Kremer L.
  Title
Phosphorylation of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier  protein reductase MabA regulates mycolic acid biosynthesis.
  Journal
J Biol Chem 285:12714-25 (2010)
DOI:10.1074/jbc.M110.105189
Reference
2  [PMID:17059223]
  Authors
Silva RG, de Carvalho LP, Blanchard JS, Santos DS, Basso LA.
  Title
Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein (ACP) reductase:  kinetic and chemical mechanisms.
  Journal
Biochemistry 45:13064-73 (2006)
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