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The Pks13/FadD32 crosstalk for the biosynthesis of mycolic acids in Mycobacterium tuberculosis.

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Portevin D, de Sousa-D'Auria C, Montrozier H, Houssin C, Stella A, Laneelle MA, Bardou F, Guilhot C, Daffe M.

The acyl-AMP ligase FadD32 and AccD4-containing acyl-CoA carboxylase are required  for the synthesis of mycolic acids and essential for mycobacterial growth:  identification of the carboxylation product and determination of the acyl-CoA  carboxylase components.

J Biol Chem 280:8862-74 (2005)

Le NH, Molle V, Eynard N, Miras M, Stella A, Bardou F, Galandrin S, Guillet V, Andre-Leroux G, Bellinzoni M, Alzari P, Mourey L, Burlet-Schiltz O, Daffe M, Marrakchi H.

Ser/Thr Phosphorylation Regulates the Fatty Acyl-AMP Ligase Activity of FadD32,  an Essential Enzyme in Mycolic Acid Biosynthesis.

J Biol Chem 291:22793-22805 (2016)