KEGG   REACTION: R13275
Entry
R13275                      Reaction                               
Definition
Meromycoloyl-[acp] + Very-long-chain alpha-carboxyacyl-CoA + alpha,alpha-Trehalose <=> Trehalose mycolic-beta-ketoester + CoA + CO2 + Acyl-carrier protein
Equation
Comment
general reaction
Orthology
K12437  polyketide synthase 13
Reference
1  [PMID:25467124]
  Authors
Gavalda S, Bardou F, Laval F, Bon C, Malaga W, Chalut C, Guilhot C, Mourey L, Daffe M, Quemard A.
  Title
The polyketide synthase Pks13 catalyzes a novel mechanism of lipid transfer in  mycobacteria.
  Journal
Chem Biol 21:1660-9 (2014)
DOI:10.1016/j.chembiol.2014.10.011
Reference
2  [PMID:27268593]
  Authors
Quemard A.
  Title
New Insights into the Mycolate-Containing Compound Biosynthesis and Transport in  Mycobacteria.
  Journal
Trends Microbiol 24:725-738 (2016)
DOI:10.1016/j.tim.2016.04.009
Reference
3  [PMID:14695899]
  Authors
Portevin D, De Sousa-D'Auria C, Houssin C, Grimaldi C, Chami M, Daffe M, Guilhot C.
  Title
A polyketide synthase catalyzes the last condensation step of mycolic acid  biosynthesis in mycobacteria and related organisms.
  Journal
Proc Natl Acad Sci U S A 101:314-9 (2004)
Reference
4  [PMID:19436070]
  Authors
Gavalda S, Leger M, van der Rest B, Stella A, Bardou F, Montrozier H, Chalut C, Burlet-Schiltz O, Marrakchi H, Daffe M, Quemard A
  Title
The Pks13/FadD32 crosstalk for the biosynthesis of mycolic acids in Mycobacterium tuberculosis.
  Journal
J Biol Chem 284:19255-64 (2009)
DOI:10.1074/jbc.M109.006940
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