KEGG   REACTION: R13278
Entry
R13278                      Reaction                               
Name
trehalose monomycolate:AGP 5-mycolyltransferase
Definition
Trehalose monomycolate + AGP <=> alpha,alpha-Trehalose + mAGP
Equation
Comment
general reaction
Enzyme
2.3.1.-
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.-
     R13278  Trehalose monomycolate + AGP <=> alpha,alpha-Trehalose + mAGP
Orthology
K18851  diacylglycerol O-acyltransferase / trehalose O-mycolyltransferase [EC:2.3.1.20 2.3.1.122]
Reference
1  [PMID:15653820]
  Authors
Takayama K, Wang C, Besra GS.
  Title
Pathway to synthesis and processing of mycolic acids in Mycobacterium  tuberculosis.
  Journal
Clin Microbiol Rev 18:81-101 (2005)
Reference
2  [PMID:25028517]
  Authors
Backus KM, Dolan MA, Barry CS, Joe M, McPhie P, Boshoff HI, Lowary TL, Davis BG, Barry CE 3rd.
  Title
The three Mycobacterium tuberculosis antigen 85 isoforms have unique substrates  and activities determined by non-active site regions.
  Journal
J Biol Chem 289:25041-53 (2014)
DOI:10.1074/jbc.M114.581579
Reference
3  [PMID:31728063]
  Authors
Dulberger CL, Rubin EJ, Boutte CC.
  Title
The mycobacterial cell envelope - a moving target.
  Journal
Nat Rev Microbiol 18:47-59 (2020)
DOI:10.1038/s41579-019-0273-7
Reference
4  [PMID:29352107]
  Authors
Goins CM, Dajnowicz S, Smith MD, Parks JM, Ronning DR.
  Title
Mycolyltransferase from Mycobacterium tuberculosis in covalent complex with  tetrahydrolipstatin provides insights into antigen 85 catalysis.
  Journal
J Biol Chem 293:3651-3662 (2018)
DOI:10.1074/jbc.RA117.001681
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