Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446: Aaci_2443
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Entry
Aaci_2443 CDS
T00985
Name
(GenBank) squalene-hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
aac
Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446
Pathway
aac00909
Sesquiterpenoid and triterpenoid biosynthesis
aac01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
aac00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
Aaci_2443
Enzymes [BR:
aac01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
Aaci_2443
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
Aaci_2443
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Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
Prenyltrans
TED_complement
Pec_lyase
Motif
Other DBs
NCBI-ProteinID:
ACV59449
UniProt:
P33247
Structure
PDB
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Position
complement(2506260..2508155)
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AA seq
631 aa
AA seq
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MAEQLVEAPAYARTLDRAVEYLLSCQKDEGYWWGPLLSNVTMEAEYVLLCHILDRVDRDR
MEKIRRYLLHEQREDGTWALYPGGPPDLDTTIEAYVALKYIGMSRDEEPMQKALRFIQSQ
GGIESSRVFTRMWLALVGEYPWEKVPMVPPEIMFLGKRMPLNIYEFGSWARATVVALSIV
MSRQPVFPLPERARVPELYETDVPPRRRGAKGGGGWIFDALDRALHGYQKLSVHPFRRAA
EIRALDWLLERQAGDGSWGGIQPPWFYALIALKILDMTQHPAFIKGWEGLELYGVELDYG
GWMFQASISPVWDTGLAVLALRAAGLPADHDRLVKAGEWLLDRQITVPGDWAVKRPNLKP
GGFAFQFDNVYYPDVDDTAVVVWALNTLRLPDERRRRDAMTKGFRWIVGMQSSNGGWGAY
DVDNTSDLPNHIPFCDFGEVTDPPSEDVTAHVLECFGSFGYDDAWKVIRRAVEYLKREQK
PDGSWFGRWGVNYLYGTGAVVSALKAVGIDTREPYIQKALDWVEQHQNPDGGWGEDCRSY
EDPAYAGKGASTPSQTAWALMALIAGGRAESEAARRGVQYLVETQRPDGGWDEPYYTGTG
FPGDFYLGYTMYRHVFPTLALGRYKQAIERR
NT seq
1896 nt
NT seq
+upstream
nt +downstream
nt
atggctgagcagttggtggaagcgccggcctacgcgcggacgctggatcgcgcggtggag
tatctcctctcctgccaaaaggacgaaggctactggtgggggccgcttctgagcaacgtc
acgatggaagcggagtacgtcctcttgtgccacattctcgatcgcgtcgatcgggatcgc
atggagaagatccggcggtacctgttgcacgagcagcgcgaggacggcacgtgggccctg
tacccgggtgggccgccggacctcgacacgaccatcgaggcgtacgtcgcgctcaagtat
atcggcatgtcgcgcgacgaggagccgatgcagaaggcgctccggttcattcagagccag
ggcgggatcgagtcgtcgcgcgtgttcacgcggatgtggctggcgctggtgggagaatat
ccgtgggagaaggtgcccatggtcccgccggagatcatgttcctcggcaagcgcatgccg
ctcaacatctacgagtttggctcgtgggctcgggcgaccgtcgtggcgctctcgattgtg
atgagccgccagccggtgttcccgctgcccgagcgggcgcgcgtgcccgagctgtacgag
accgacgtgcctccgcgccggcgcggcgccaagggagggggtgggtggatcttcgacgcg
ctcgaccgggcgctgcacgggtatcagaagctgtcggtgcacccgttccgccgcgcggcc
gagatccgcgccttggactggttgctcgagcgccaggccggagacggcagctggggcggg
attcagccgccttggttttacgcgctcatcgcgctcaagattctcgacatgacgcagcat
ccggcgttcatcaagggctgggaaggtctagagctgtacggcgtggagctggattacgga
ggatggatgtttcaggcttccatctcgccggtgtgggacacgggcctcgccgtgctcgcg
ctgcgcgctgcggggcttccggccgatcacgaccgcttggtcaaggcgggcgagtggctg
ttggaccggcagatcacggttccgggcgactgggcggtgaagcgcccgaacctcaagccg
ggcgggttcgcgttccagttcgacaacgtgtactacccggacgtggacgacacggccgtc
gtggtgtgggcgctcaacaccctgcgcttgccggacgagcgccgcaggcgggacgccatg
acgaagggattccgctggattgtcggcatgcagagctcgaacggcggttggggcgcctac
gacgtcgacaacacgagcgatctcccgaaccacatcccgttctgcgacttcggcgaagtg
accgatccgccgtcagaggacgtcaccgcccacgtgctcgagtgtttcggcagcttcggg
tacgatgacgcctggaaggtcatccggcgcgcggtggaatatctcaagcgggagcagaag
ccggacggcagctggttcggtcgttggggcgtcaattacctctacggcacgggcgcggtg
gtgtcggcgctgaaggcggtcgggatcgacacgcgcgagccgtacattcaaaaggcgctc
gactgggtcgagcagcatcagaacccggacggcggctggggcgaggactgccgctcgtac
gaggatccggcgtacgcgggtaagggcgcgagcaccccgtcgcagacggcctgggcgctg
atggcgctcatcgcgggcggcagggcggagtccgaggccgcgcgccgcggcgtgcaatac
ctcgtggagacgcagcgcccggacggcggctgggatgagccgtactacaccggcacgggc
ttcccaggggatttctacctcggctacaccatgtaccgccacgtgtttccgacgctcgcg
ctcggccgctacaagcaagccatcgagcgcaggtga
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