Alteromonas australica H 17: EP13_09935
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Entry
EP13_09935 CDS
T03220
Name
(GenBank) 3-methyl-2-oxobutanoate dehydrogenase
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
aal
Alteromonas australica H 17
Pathway
aal00280
Valine, leucine and isoleucine degradation
aal00640
Propanoate metabolism
aal00785
Lipoic acid metabolism
aal01100
Metabolic pathways
aal01110
Biosynthesis of secondary metabolites
aal01210
2-Oxocarboxylic acid metabolism
Module
aal_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
aal00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
EP13_09935
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
EP13_09935
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
EP13_09935
Enzymes [BR:
aal01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
EP13_09935
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
DUF5805
Motif
Other DBs
NCBI-ProteinID:
AIF98972
UniProt:
A0A075P6R8
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Position
2205571..2206758
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AA seq
395 aa
AA seq
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MKDRNHLAQVTTVADVNIIDNGIIDIPMLQILDENGKATPEATLPDISQAQALKIHETMA
YTRVLDERMVAAQRQGRISFYLASTGEEAATVASAAALSTEDLIMSQYREQGALAYRGYT
TDQFMNQMFSNKDDPNKGRQMPIHYGDKALNFMTISSPLGTQIPQASGYAYGQKMAGKDA
ITICYFGEGAASEGDFHAGLNMAAVLSCPVIFFCRNNGYAISTPAEEQFAGDGIASRGLG
YGIKTIRVDGNDVLAVYAATKRAREIALAEQCPVLIEAMTYRLAAHSTSDDPSGYRSKEE
EEKWRTKDPITRFANWLTHKGWFNEQDNEKRLTAMRQEVLASMKRCETTEICPIDDIVSD
VYDSVPWHLDEQLQDLKQHIKKYPHMYPKTSGRMK
NT seq
1188 nt
NT seq
+upstream
nt +downstream
nt
atgaaagacagaaaccacctagcacaagtaacaactgttgccgatgtgaatattatagat
aacggtattattgacatcccaatgctgcaaattctcgacgaaaacggtaaagcaacgccg
gaggcaaccttacccgacattagtcaagcgcaagcgttaaagattcacgagaccatggcc
tacacgcgggtgcttgatgaacgaatggtggcggctcaacgccaagggcgtattagcttt
taccttgcaagtaccggcgaggaagccgcaacggtagcaagcgcagcggcactaagtacc
gaagacctcatcatgtcacaatatcgtgagcaaggggcattggcttatcgaggatacacc
actgatcaattcatgaatcagatgttcagcaataaagacgaccctaataaaggccgccaa
atgccgattcattatggtgataaagcgctaaatttcatgacgatctcatctccccttggc
acccaaataccgcaagcttccggctatgcgtatggtcaaaaaatggcagggaaagacgca
attaccatatgctatttcggagaaggtgccgcgtcagaaggagatttccacgctgggctt
aatatggcagcggtacttagctgtcctgtcatctttttttgcagaaataatggctacgct
atctccacaccagcagaggaacaatttgcaggtgatggcatagcgtctcgcgggttaggt
tacggaataaaaaccattcgggtagacggcaacgacgtattagcggtttacgcggcaacg
aaacgggcgagggaaatcgctcttgcagaacaatgccctgtacttattgaagcgatgacc
tacaggttagccgcccattctacctccgatgatcctagcggttaccgctcaaaagaagag
gaagaaaaatggcgcacaaaagaccctattactcggtttgccaactggttaacccacaaa
ggctggtttaacgaacaagacaatgaaaaacgccttaccgcaatgcgccaagaggtttta
gcgtcaatgaagcggtgcgaaaccaccgaaatttgtcctatcgatgacattgtgagtgat
gtctatgattcagtgccttggcaccttgatgaacaacttcaagaccttaaacaacacatt
aaaaaatacccacacatgtaccctaaaacgtcagggagaatgaaataa
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