Arvicola amphibius (Eurasian water vole): 119801461
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Entry
119801461 CDS
T08327
Symbol
Pdha2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
aamp
Arvicola amphibius (Eurasian water vole)
Pathway
aamp00010
Glycolysis / Gluconeogenesis
aamp00020
Citrate cycle (TCA cycle)
aamp00620
Pyruvate metabolism
aamp00785
Lipoic acid metabolism
aamp01100
Metabolic pathways
aamp01200
Carbon metabolism
aamp01210
2-Oxocarboxylic acid metabolism
aamp04066
HIF-1 signaling pathway
aamp04922
Glucagon signaling pathway
aamp05230
Central carbon metabolism in cancer
aamp05415
Diabetic cardiomyopathy
Module
aamp_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
aamp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
119801461 (Pdha2)
00020 Citrate cycle (TCA cycle)
119801461 (Pdha2)
00620 Pyruvate metabolism
119801461 (Pdha2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
119801461 (Pdha2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
119801461 (Pdha2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
119801461 (Pdha2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
119801461 (Pdha2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
119801461 (Pdha2)
Enzymes [BR:
aamp01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
119801461 (Pdha2)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
119801461
NCBI-ProteinID:
XP_038167997
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Position
14:complement(47119371..47120546)
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AA seq
391 aa
AA seq
DB search
MRKMLAAVVSHVFSGVTQKPAMRGVLASLNFSNDATCDIKKCDLYRLEEGPPTSTVLTRE
EALKYYRTMQVIRRMELKSDQMYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHVITSYR
AHGLCYTRGLSVKSILAELTGRRGGCAKGKGGSMHMYGKHFYGGNGIVGAQVPLGAGIAF
ACKYLGNGQVCLALYGDGAANQGQVAEAYNISALWKLPCVFICENNRYGMGTAVERAAAS
TDYHKRGNFIPGLRVNGMDILSVREATKFAADHCRSGKGPILMELQTYRYHGHSMSDPGV
SYRSREEVHNMRSKSDPIMLLRERMINNNLSNVEELKEIDADVRKEVEEAAQFATTDPEP
TLEELAHHIYYRNPPFEVRGTNKWIKYKSVS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctggccgctgtggtgtcgcacgtgttttcgggagtgacccagaagccg
gctatgagaggggtgctggcgtccctgaacttctccaacgacgccacctgcgacattaag
aaatgcgatctgtaccggctggaagagggccctccgacgtccaccgtgctcacccgagag
gaggccctcaaatactaccggaccatgcaggtgattcggcgcatggagctgaagtctgac
cagatgtacaagcagaagttcattcgtggtttctgtcacctgtgtgacggtcaggaagcc
tgctgcgtggggctggaggcggggatcaatcccacggatcatgtcatcacgtcctaccgg
gctcatggcttgtgctacacgcgggggctgtcggtcaaatccattctcgccgagctgacc
ggacgccgaggaggctgcgccaagggcaaaggaggctcgatgcacatgtacggcaagcac
ttctacgggggcaatggcatcgtcggggcacaggtacccctgggagccggtatcgctttc
gcctgtaaatacttgggaaatggtcaggtctgcctggctctatatggcgacggtgcagct
aaccaggggcaggtagccgaagcttacaatatatcggccttgtggaaattaccttgtgtc
ttcatctgtgagaataaccgctacggaatggggacggccgttgagcgagcagcagccagc
actgattaccacaagagaggcaattttatccctggactgagggtgaatggaatggatatc
ctctctgtccgggaggcgaccaagtttgcagctgatcactgcagatctggtaaggggccc
attttgatggaactgcagacctaccgttatcatggacacagtatgagtgacccgggggtc
agttaccgttcacgagaagaagttcacaatatgcgaagtaagagtgaccctattatgctt
ctccgagagagaatgataaacaacaacctcagcaacgttgaagagttgaaggagatcgat
gcagatgtgagaaaagaagttgaggaagcagcccagtttgctacaactgatccagaacca
actttggaagaattagctcatcacatctactaccgcaatccaccttttgaagttcgtggt
acaaataaatggatcaagtataagtctgtcagttag
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