Arvicola amphibius (Eurasian water vole): 119820587
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Entry
119820587 CDS
T08327
Symbol
Map3k5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
aamp
Arvicola amphibius (Eurasian water vole)
Pathway
aamp01524
Platinum drug resistance
aamp04010
MAPK signaling pathway
aamp04071
Sphingolipid signaling pathway
aamp04141
Protein processing in endoplasmic reticulum
aamp04210
Apoptosis
aamp04530
Tight junction
aamp04668
TNF signaling pathway
aamp04714
Thermogenesis
aamp04722
Neurotrophin signaling pathway
aamp04932
Non-alcoholic fatty liver disease
aamp04936
Alcoholic liver disease
aamp05010
Alzheimer disease
aamp05012
Parkinson disease
aamp05014
Amyotrophic lateral sclerosis
aamp05016
Huntington disease
aamp05017
Spinocerebellar ataxia
aamp05022
Pathways of neurodegeneration - multiple diseases
aamp05208
Chemical carcinogenesis - reactive oxygen species
aamp05417
Lipid and atherosclerosis
aamp05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
aamp00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
119820587 (Map3k5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
119820587 (Map3k5)
04668 TNF signaling pathway
119820587 (Map3k5)
04071 Sphingolipid signaling pathway
119820587 (Map3k5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
119820587 (Map3k5)
09144 Cellular community - eukaryotes
04530 Tight junction
119820587 (Map3k5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
119820587 (Map3k5)
09159 Environmental adaptation
04714 Thermogenesis
119820587 (Map3k5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
119820587 (Map3k5)
09164 Neurodegenerative disease
05010 Alzheimer disease
119820587 (Map3k5)
05012 Parkinson disease
119820587 (Map3k5)
05014 Amyotrophic lateral sclerosis
119820587 (Map3k5)
05016 Huntington disease
119820587 (Map3k5)
05017 Spinocerebellar ataxia
119820587 (Map3k5)
05022 Pathways of neurodegeneration - multiple diseases
119820587 (Map3k5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
119820587 (Map3k5)
05418 Fluid shear stress and atherosclerosis
119820587 (Map3k5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
119820587 (Map3k5)
04932 Non-alcoholic fatty liver disease
119820587 (Map3k5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
119820587 (Map3k5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
aamp01001
]
119820587 (Map3k5)
Enzymes [BR:
aamp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
119820587 (Map3k5)
Protein kinases [BR:
aamp01001
]
Serine/threonine kinases: STE group
STE11 family
119820587 (Map3k5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
FPP
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
119820587
NCBI-ProteinID:
XP_038195001
LinkDB
All DBs
Position
8:28341181..28552168
Genome browser
AA seq
1380 aa
AA seq
DB search
MGTEAGEGITFSVPPFASAGFCTIPEGGSCRRGGGAATAVEGEPSHLPLSPQPPPPPGSF
WNVESAAAPGTGCPATTPGNSTTRGRGNSGSGGGRRTTVAYVINEASQGQLVVAESEALQ
SLREACEVVGATLETLHFGKLDFGETAVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRES
FSMADNIILYCDANSDSLQSLKEIICQKNTMCTGNYTFVPYMVTPHNKVYCCDSSFMKGL
TELMQPNFELLLGPICLPLVDRFVQLLKVAQASSSQYFRESILNDIRKARNLFTGKELAA
ELARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFH
YAFALNRRNLPGDRAKALDIMIPMVQSEGQVASDMYCLVGRIYKDMFLDSNFTDTESRDH
GASWFKKAFESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQS
YWEVGFFLGASVLANDHLRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTTEQPMA
KQELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPD
DKKGIHEWNFSASSIRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTIT
EEKGRGTEDGDCEGDSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPER
DSRYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLK
DNEQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINP
CTETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKV
GMFKVHPEIPESMSAEAKAFILKCFEPDPDKRACANDLLVDEFLKVSSKKKKTQPKLSAL
STGSNEYLRSISLPVPVLVEDTSSSSEYGSVSPDTELKGDPFSFKARAKSCGEKDAKGIR
TLFLGIPDENFEDHSAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLA
QGAEEPKLKWEHITTLIASLREFVRSTDRKIIATTLSKLKLELDFDSHGINQVQVVLFGF
QDAVNKVLRNHNIKPHWMFALDSIIRKAVQTAITTLVPELRPHFSLASESDTADPEDLDV
EDEHEESPSNQNVRRPQAVIEDAVATSGVSTLSSTVSHDSQSAHRSLNVQLGRMKIETNR
LLEELVRKEKELQALLHQAIEEKDQEIKHLKLKSQPIDIPGFPTRRLNSAGTTTEDSELT
GWLRDNGADEDTISRFLAEDYTLVDVLYYVTRDDLKYLRLRGGMLCTLWKAIADFRDKRA
NT seq
4143 nt
NT seq
+upstream
nt +downstream
nt
atgggcaccgaagccggcgagggcatcactttctccgtgccgccctttgcgtccgcgggc
ttttgcaccatcccggagggcggcagctgccggaggggaggaggagcggcgacggcggtg
gagggcgagccgagccatctgcctctgtcgccacagccaccgccaccgccgggcagtttc
tggaacgtggagagcgcggccgctcctggcaccgggtgccctgctaccacccccgggaac
agcaccacccgaggccgaggcaactctggaagcgggggcggccggaggaccaccgtggca
tatgtgatcaacgaggcaagccaggggcagctggtggtggccgagagcgaggccctgcag
agcctgcgggaggcgtgtgaggtggtgggcgccaccctggagaccctgcattttgggaaa
ctggacttcggggaaaccgccgtgctggaccgtttctacaatgcagacatcgcggtggtg
gagatgagcgacgccttccggcagccatccttattttaccaccttggggtgagagagagc
ttcagtatggccgacaacatcatcctctactgtgacgccaactccgactcgcttcagtcc
ctgaaggaaatcatttgccagaagaatactatgtgcacggggaactacaccttcgtccct
tacatggtgacgccacataacaaggtctactgctgtgacagcagcttcatgaagggcctg
actgagctcatgcagcccaacttcgagctcttgctgggacccatctgcctgcctctcgtg
gatcgtttcgttcagcttctgaaggtggcgcaggccagttccagccagtactttcgggaa
tctatactcaatgatatcaggaaagctcggaacctattcactggtaaagaattggcggcg
gaactggcaaggattcggcagcgagtggacaatattgaagttttgacggcagacatcgtc
atcaacctgttgctttcctaccgagatatccaggactatgactctattgtgaagctggta
gagacgctagagaagctgccgaccttcgatctggcctcgcatcaccatgtgaagtttcat
tacgcattcgccctgaacaggagaaatctccctggagacagagccaaagctcttgacatc
atgatccccatggtacagagtgaagggcaagtggcttcagatatgtattgcctcgttggc
cgaatctacaaagatatgtttttggattccaacttcactgacactgaaagcagggaccat
ggagcatcctggttcaaaaaggcatttgagtctgagccaacactacagtcaggaattaat
tatgcagtcctcttgctggcggctgggcaccagtttgaatcctcctttgagcttcggaaa
gttggggtgaagctgagcagcctgctgggtaaaaaggggaacctggaaaaactccagagc
tactgggaagtcggcttctttctgggagccagcgtcctggccaatgaccacctgcgcgtc
attcaagcatctgagaagctgtttaaactgaagacaccagcatggtacctcaagtctatt
gtggagacaattttgatatataagcattttgtgaaactgaccacggagcagcccatggcc
aagcaggaactcgtggacttttggatggatttcctggttgaggccaccaaaaccgatgtt
accgtcgttagatttccagtattaatattagagccaaccaaaatctatcagccttcctac
ctgtctatcaataacgaagtcgaggagaagacaatatctatttggcacgtgcttcctgat
gacaagaaaggtatacatgaatggaacttcagtgcgtcctctatcaggggagtaagtatc
tccaagtttgaagagcgctgctgctttctttacgtgcttcacaattcggatgacttccag
atctacttctgtacagagctgcactgtaaaaagttctttgaaatggtgaataccattaca
gaagagaagggcagaggcacggaggatggagactgtgaaggggactccttggagtatgac
tatgaatacgacgagaacggtgaccgcgtcgtgctaggaaaaggcacgtacgggatcgtc
tatgcaggtcgagacctgagcaaccaggtcagaattgctattaaggaaatcccagagaga
gacagcagatactcgcagcccctgcatgaagaaattgccttgcacaagcatctgaagcac
aaaaacattgtccagtatctgggctccttcagtgagaacggcttcattaaaatcttcatg
gagcaagtcccaggaggaagtctttccgctctccttcgttccaaatggggcccattaaaa
gacaatgagcaaacgattggcttctatacaaagcaaatactggaaggattaaaatacctt
catgacaatcagatagttcaccgggatataaagggtgacaatgtattgattaatacctac
agtggtgttctcaagatctctgacttcgggacatcaaagaggcttgctggcataaatccc
tgtaccgaaacctttacaggtaccctgcagtatatggcaccagaaataatcgataaagga
ccacgaggctatgggaaagccgcggacatttggtctttgggctgcactatcatcgaaatg
gccactggaaagccgccattttatgaactaggagagccgcaagcagccatgttcaaggtg
gggatgttcaaggtccacccagagatcccagagtccatgtcggctgaggccaaggcattc
atcctgaagtgttttgaaccagaccctgacaagagagcctgtgctaatgacttgctcgtt
gacgagttcttaaaagtttccagcaaaaagaaaaagacacaacccaagctttcggctctc
tcgactggatcgaatgaatatctcagaagtatctccctgccggtccctgtcctggtggaa
gacaccagcagcagcagtgagtatggctcagtttctcctgacacggagctgaagggggac
cccttctcgttcaaagccagagccaagtcctgcggggagaaggatgcgaaagggatacgg
acactctttctgggcattccagatgaaaactttgaagaccacagtgcgcccccttccccc
gaggagaaagactccggcttctttatgctgagaaaggatagcgaaaggcgggccaccctc
cacaggatcctgacggaagaccaggacaaggtcgtgcggaacctgatggaatcgctggcc
cagggtgctgaagagcctaaactcaaatgggaacacatcacgaccctcatcgcgagcctc
agagagtttgtgaggtccactgaccgaaaaatcatcgccactacactgtcaaagctgaaa
ctggagctggacttcgacagccacggcatcaaccaggtgcaggtggtcctcttcggcttc
caggatgcggtcaataaagttcttcggaatcataacatcaagccacactggatgtttgcc
ttggacagtatcattcgaaaggctgtgcaaacagctattaccactctggttccagagctg
aggccacattttagcctcgcttctgagagcgacacagccgatccggaagacttggatgtc
gaagatgaacacgaggaatccccttcgaatcaaaatgtccggagacctcaggccgtcatc
gaggatgctgtggcgacctcgggggtgagcacgctcagctccactgtgtcccacgattcc
cagagcgctcaccggtctctgaatgtgcagcttggaaggatgaaaatagaaactaataga
ttacttgaagagttagtgcggaaagagaaagagttacaagcactcctccatcaagctatt
gaagaaaaagaccaagaaatcaaacacctgaagcttaagtcccagcccatagatatccct
gggtttcccacgcgccgcctgaactctgctggcacaaccactgaagattctgaacttact
ggctggctgagagacaatggagctgacgaagacactatcagtcggtttctggctgaggat
tacacgctcgtggatgttctctactacgtgacacgtgatgatttaaagtacctcagacta
aggggagggatgctgtgcacgctgtggaaggccatcgctgactttcgggacaaacgcgcc
tga
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