Actinomyces capricornis: MANAM107_02260
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Entry
MANAM107_02260 CDS
T09393
Name
(GenBank) dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
acap
Actinomyces capricornis
Pathway
acap00790
Folate biosynthesis
acap01100
Metabolic pathways
acap01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
acap00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
MANAM107_02260
Enzymes [BR:
acap01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
MANAM107_02260
6.3.2.17 tetrahydrofolate synthase
MANAM107_02260
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
BDA63392
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Position
complement(267330..269177)
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AA seq
615 aa
AA seq
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MSQEKNRPEDGADHPGAAFGIPRGATGEEVVDAVFGQGVGAPGAGGAEGIDPELLPYLEA
AGTEGARMSLTEAEQEALEAQAAAEAQEQEDREALRALVAANLIPGGDMDRLEELLAQAD
ADDSDDWESWEPQLPEAPAPGLSEEEVHRRELQEAARSIEVAERMRQVEAQILARAPEHQ
VQPSLERVEMVLDILGNPERGYRTVHITGTNGKTSTARMAERLLAATGMRTGRFTSPHLA
SIRERIALDGEPISPEGFIAAWEDVAPYIEMVDERSQAAGGPRLSFFEVLTVMALAAFAD
HPVDVAIIEVGMGGRWDATNVIPADIAVITPVGRDHERWLGASLSRIAAEKAGVIKEGGW
LVTAHQVPEVRAEIEAALAAHRAVEWRELDPQEDPAEAGPGTMEVGERQVAVGGQLVTLR
TPAAVYQDVFVPLHGEYQAHNALLALAAAEAVFGGSALAPRVVEEGLSSVTSPGRLEVLR
SSPSVLVDAAHNPHGVEALVAAVEEVFGFRHLVAVVGAMADKDVEGILAGLEPVTDAVVC
VPIDTPRAMEVADLAEIAREVYGAERVVVAETLGEGVEQAVSLSEGFDAPMTASGVLIVG
SVILAAQARALFGCA
NT seq
1848 nt
NT seq
+upstream
nt +downstream
nt
atgagtcaagagaagaaccggcccgaggacggggccgaccacccgggagcggccttcggc
atccccaggggggccaccggtgaggaggtcgtcgacgccgtcttcgggcagggcgtcgga
gcgccgggagccgggggggcggagggcatcgaccccgagctcctgccctacctggaggct
gcgggcaccgagggcgccaggatgtccctgaccgaggccgagcaggaggcgctggaggcc
caggccgccgccgaggcccaggagcaggaggaccgcgaggcgctgcgcgccctggtggcg
gccaacctcatccccggaggggacatggaccgcctcgaggagctcctggcccaggccgac
gccgatgacagcgacgactgggagtcctgggagccccagctgcccgaggcccccgccccc
gggctcagcgaggaggaggtccaccgccgcgagctccaggaggccgcgcgctccatcgag
gtcgccgagcgcatgcgccaggtcgaggcccagatcctggcccgcgcccccgagcaccag
gtccagccctccctggagcgggtcgagatggtcctggacatcctgggcaatcccgagcgc
ggctaccgcaccgtccatatcaccggcaccaacggcaagacctcgacggcccgcatggcc
gagcgcctcctggcggccaccggtatgcgcaccggccgcttcacctccccccacctggcc
tccatccgcgagcgcatcgccctggacggcgagccgatcagccccgagggcttcatcgcc
gcctgggaggacgtggccccctatatcgagatggtcgatgagcgctcccaggccgccggc
gggccgcgcctgtccttcttcgaggtgctcacggtcatggccctggcggccttcgccgac
catcccgtggatgtggccatcatcgaggtgggcatgggcgggcgctgggacgccaccaat
gtcatccccgccgatatcgccgtcatcacgccggtggggcgagaccatgagcgctggctg
ggcgcctccctgagccggattgccgcggagaaggcgggtgtcatcaaggagggcggctgg
ctcgtcaccgcccaccaggtcccggaggtgcgcgccgagatcgaggcggcgctggctgcg
caccgcgcggtggagtggcgcgagctcgacccccaggaggatcccgctgaggcggggccg
ggcaccatggaggtgggggagcgtcaggtggcggtcggcggccagctggtcacgctgcgc
acgcccgcggcggtctaccaggatgtcttcgtgcccctgcacggggagtaccaggcccac
aacgccctgctggccctggcggccgccgaggcggtcttcggcggctcggcgctggcgccg
cgggtggtggaggagggcctgtcctcagtgaccagccccgggcgcctggaggtgctgcgc
tcctcgccctcggtgctggtcgacgccgcccacaatccgcatggggtcgaggccctggtg
gcggcggtggaggaggtcttcggcttccgtcatctggtggccgtggtgggcgcgatggcc
gataaggatgtcgaggggatcctggcgggtctggagccggtgaccgatgccgtcgtgtgc
gtgcccatcgatacgccgcgggccatggaggtcgccgatctggccgagatcgcccgggag
gtctatggcgctgagcgcgtcgtggtcgctgagaccctgggggagggggtggagcaggcg
gtctcgctgtccgagggcttcgatgccccgatgacggcctcgggcgtgctcatcgtgggc
tcggtgatcctggcggcgcaggccagggccctgttcggctgcgcctga
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