Actinomadura sp. WMMB 499: F7P10_06385
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Entry
F7P10_06385 CDS
T06213
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
actw
Actinomadura sp. WMMB 499
Pathway
actw00010
Glycolysis / Gluconeogenesis
actw00020
Citrate cycle (TCA cycle)
actw00620
Pyruvate metabolism
actw00785
Lipoic acid metabolism
actw01100
Metabolic pathways
actw01110
Biosynthesis of secondary metabolites
actw01120
Microbial metabolism in diverse environments
actw01200
Carbon metabolism
actw01210
2-Oxocarboxylic acid metabolism
Module
actw_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
actw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
F7P10_06385 (pdhA)
00020 Citrate cycle (TCA cycle)
F7P10_06385 (pdhA)
00620 Pyruvate metabolism
F7P10_06385 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
F7P10_06385 (pdhA)
Enzymes [BR:
actw01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
F7P10_06385 (pdhA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
QFG20826
UniProt:
A0A5J6U2S2
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All DBs
Position
1473817..1474974
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AA seq
385 aa
AA seq
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MAETTRSAGTAAPARTSRTRGAKASGRETGRAATPAPGADVPAGSASGSGADAETLIGYY
RQMLLIRRFEERAARAYTEAKIGGYCHLNLGEEATVVGLMAALRPTDYLFTNYREHGYAI
AKGITPDRVMAELYGRSTGVSKGWGGSMHMFDKEARLLGGYGIVGGQVPLATGAALAVGY
KGGDDVVMCQMGDGTAAIGAFHESLNIAGLWDLPAVFVVINNGLGMGTTVENSSAEPELY
KRGAAYRMESARVDGTDVVAVRDAAVLAVEKARADSRPYLLETISPRLKGHSVVDPARYR
SKEERDALKAADPLARIALDLAERGILSHDARDALDAEVTAEVDAAAAFADGSPAPDVST
LFDYTYATPVPGELRRLPADPVFSS
NT seq
1158 nt
NT seq
+upstream
nt +downstream
nt
atggctgagacgacccggtcggccggcactgccgccccggcccgcaccagcagaacgcgc
ggcgccaaggcgtccgggcgcgagaccggccgcgcggcgacgcccgcgccgggcgccgac
gtcccggcgggcagcgcgtccggttcgggcgccgacgcggagacgctcatcggttactac
cggcagatgctgctgatccgccggttcgaggagcgcgccgcccgcgcctacaccgaggcg
aagatcggcggctactgccacctgaacctcggggaggaggccacggtcgtcgggctgatg
gccgcgctgcggcccaccgactacctgttcacgaactaccgcgagcacggctacgcgatt
gccaagggcatcacccccgaccgggtgatggccgagctgtacggccgctccaccggcgtg
tccaagggctggggcgggtcgatgcacatgttcgacaaggaggcccggctgctcggcggg
tacggcatcgtcggcggccaggtgccgctcgccacgggcgcggcgctcgccgtcggctac
aagggcggcgacgacgtcgtcatgtgccagatgggcgacgggacggccgcgatcggcgcg
ttccacgagtcgctgaacatcgcgggcctgtgggacctgcccgccgtgttcgtcgtcatc
aacaacgggctgggcatgggcaccaccgtggagaactcctccgccgagcccgagctgtac
aagcgcggcgccgcctaccggatggagtccgcccgcgtcgacgggacggacgtcgtcgcc
gtgcgggacgccgccgtgctggccgtcgagaaggcccgcgcggacagccgcccgtacctg
ctggagaccatcagcccccggctgaagggccactcggtcgtcgacccggcccgctaccgc
tccaaggaggagcgggatgcgctcaaggccgccgacccgctggcccgcatcgcgctggac
ctcgccgagcgcgggatcctgtcgcacgacgcgcgggacgcgctggacgccgaggtcacc
gccgaggtcgacgccgcggcggcgttcgccgacgggtccccggcgccggacgtctccacg
ctgttcgactacacctacgccaccccggtcccgggcgagctgcgccgcctgcccgcggac
cccgtattcagttcctga
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