Actinomyces sp. 432: CWT12_08165
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Entry
CWT12_08165 CDS
T06433
Name
(GenBank) tetrahydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
actz
Actinomyces sp. 432
Pathway
actz00790
Folate biosynthesis
actz01100
Metabolic pathways
actz01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
actz00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
CWT12_08165
Enzymes [BR:
actz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
CWT12_08165
6.3.2.17 tetrahydrofolate synthase
CWT12_08165
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
DUF6158
Motif
Other DBs
NCBI-ProteinID:
QHO91291
UniProt:
A0A7L5API6
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Position
complement(1960747..1962606)
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AA seq
619 aa
AA seq
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MSSKQRDRDAHASGQTESHPGAAFGIPAGASGEDVVDAVYGPGGTHSGIDPELLPYLEAA
DSSEGKSLAQAAEDDAAAERSREQAEAEDLAALRELVAANMVPGGDLERLDALLAEVDAD
ESDDWEDWEPVLPDVAGNGSAEDNPGADAERHRAELTAAARAVEVSARMREVEAEILSRA
PEHQVQPSLERVEAVLDILGNPERNYRIVHVAGTNGKTSTARMTERLLAATGMRTGRFTS
PHLATIRERIALDGEPISEEGFIAAWEDVAPYVEMADARSQAAGGPRLSFFEVLTVMALA
AFADHPVDVAVIETGMGGTWDSTNVVPGDVEVITPIGLDHAAWLGATVEEVAANKAGIIK
DGATLVTAAQPESVQAVIAAAAVEHQVIWRRELDPEEDPGAPDAGVLRVVDRTLGVGGQM
ATFATAAGVYEDVFVPLYGDYQAHNALLALAAAEAVFGGRQLPAKIVEDGFASVTSPGRL
EVLRSSPTVIVDAGHNPHGVTALSGAVEEAFGFQHLVAVVGLMGDKDAEGILSVLEPVCD
AVVCVPVDSPRAMDAEDLGAVAREVFGADRVVVAPTLVAGVEQAVSLSEGFDAPLTASGV
LVVGSVVLAAQARALFGRP
NT seq
1860 nt
NT seq
+upstream
nt +downstream
nt
atgagcagcaagcagcgcgatcgggacgcccacgccagcggtcagaccgagtcgcatccc
ggtgcggccttcggcattcccgccggtgccagtggcgaagacgtagtagacgccgtctac
gggcccggcggcacgcactccggcatcgatcccgagctgctgccgtacctggaagccgcc
gactcgtccgagggcaagtccctggcccaggccgccgaggacgacgccgctgccgagcgc
agccgcgagcaggccgaggcggaggacctggcggccctgcgcgagctcgtcgccgccaat
atggtgcccggcggcgacctggagcgcctggacgccctgctggccgaggtcgacgccgat
gaatccgacgactgggaggactgggaaccggtactgcccgacgtcgccgggaatggttcc
gcggaagacaatcccggggctgacgccgagcgccaccgcgccgagctgaccgcagccgcc
cgcgccgtcgaggtgtctgcgcgcatgcgcgaggtcgaggcggagatcctctcccgcgct
cccgagcaccaggtgcagccctccctggaacgcgttgaggccgtgctcgacatcctgggc
aaccccgagcgcaactaccggatcgtgcacgtggcgggcactaacggcaagacctccacc
gctcgcatgactgagcgcctgctggccgccaccggcatgcgcaccgggcgcttcaccagc
ccccacctggccaccatccgcgagcgcatcgccctggacggtgagcccatcagcgaggag
ggattcatcgccgcctgggaggacgtcgccccctacgtcgagatggcagacgcccgctcc
caggccgccgggggcccgcggctgagcttcttcgaggtactcacggtgatggcgctggcg
gccttcgccgaccatcccgtggacgtggcggtgatcgagaccggcatgggcggtacttgg
gactccaccaacgtggtgcccggcgacgtggaggtcatcactccgatcgggctcgaccac
gccgcgtggctgggcgccacggttgaggaggtcgccgccaataaggccggcatcatcaag
gacggcgccacgctggttaccgccgcgcagccggagtcggtgcaggcggtaatcgccgca
gccgccgtcgagcatcaggtcatatggcggcgggagctcgacccggaggaggatcccggg
gcccccgacgccggcgtgctccgggtggtggaccgcaccttgggcgttggcgggcagatg
gctaccttcgccaccgccgcgggcgtgtacgaggacgtgttcgtgccgctgtacggcgac
taccaggcgcataacgccttgctggcactggccgctgcggaggccgtcttcggcggtagg
cagcttcccgcgaagatcgttgaggacggattcgcctccgtgaccagccccggccgcctg
gaggtgctgcgctccagcccgacggttatcgtcgacgccggccacaacccccacggcgtt
accgccctttccggggcggtggaggaggccttcggcttccagcacctggttgccgtcgtc
ggcctcatgggggacaaggacgcggagggcattctgtcggtactggagccggtctgcgac
gccgtcgtgtgtgttccggtcgactctccacgtgccatggatgctgaggacttgggcgcg
gtggcgcgcgaggtattcggtgcggaccgggtggtggtggcgcccacgctggtggccggc
gtggagcaggcggtgagcctgtcggagggcttcgacgctccgcttaccgcctcgggcgtg
ctcgtggtcggttccgtggtgctggccgcgcaggcgcgcgccctgttcggcaggccctga
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