Aspergillus fumigatus: AFUA_3G01450
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Entry
AFUA_3G01450 CDS
T01017
Name
(RefSeq) 3-methyl-2-oxobutanoate dehydrogenase
KO
K00167
2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:
1.2.4.4
]
Organism
afm
Aspergillus fumigatus
Pathway
afm00280
Valine, leucine and isoleucine degradation
afm00640
Propanoate metabolism
afm00785
Lipoic acid metabolism
afm01100
Metabolic pathways
afm01110
Biosynthesis of secondary metabolites
afm01210
2-Oxocarboxylic acid metabolism
Module
afm_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
afm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
AFUA_3G01450
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
AFUA_3G01450
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AFUA_3G01450
Enzymes [BR:
afm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
AFUA_3G01450
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Motif
Pfam:
Transket_pyr
Transketolase_C
PFOR_II
Motif
Other DBs
NCBI-GeneID:
3506010
NCBI-ProteinID:
XP_748466
UniProt:
Q4WFP9
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Position
3:complement(368751..370038)
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AA seq
387 aa
AA seq
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MASLRPSVKRLLRQPPCRLYSGAPSSSSRLNLPIDYKSTPLLHHTSSSLSSALELPGSTT
SKSLNLYQAINSALRTALATDNRVMLFGEDVAFGGVFRCSMDLQTEFGSERVFNTPLTEQ
GIVGFAIGAAAQGMKPVAEIQFADYVFPAFDQIVNEAAKFRYREGGTGVNVGGMVVRMPC
GAVGHGALYHTQSPEALFAHVPGVQVVMPRSPSQAKGLLLSAIFQSNNPVIFMEPKILYR
AAVEHVPNEFYTLSLNKAEVVKPGNDVTVVSYGQPMYLCSEAIRAIEKDMGASVELIDLR
TIYPWDRQTVLDSVKKTGRAIVVHESMINYGVGAEVAATIQDGAFLRLEAPVKRVAGWST
HTGLTFEKLILPDVARIYDAIKQTLEY
NT seq
1164 nt
NT seq
+upstream
nt +downstream
nt
atggcttctctccgcccctctgtcaaaaggttattacgacagccgccctgccggttgtac
tcgggcgctccgtcatcctcatcacgactcaatctacccatcgactacaaatctacaccc
cttctgcatcatacctcgtcctcactatcgagcgcactagaactacctggctcaaccacc
agcaaatcactaaatctataccaagctatcaactccgcgttgcgaaccgcccttgctacg
gataacagggtgatgctgtttggcgaggatgtagcattcggcggagtgtttcgatgctcg
atggacttgcaaacggagttcggatcggagcgtgtatttaataccccgttgacggaacaa
gggattgttgggttcgctattggagctgccgcgcaaggcatgaagcctgttgccgagatc
caattcgccgattatgtttttcctgcttttgaccagattgtgaacgaagctgcaaagttc
aggtaccgagagggaggtacaggcgtaaatgtggggggaatggtggtccgaatgccctgt
ggtgcagtcggacacggcgccctataccatacacaatcccccgaagcgcttttcgctcat
gttcccggtgtccaagtggtcatgcctcggtctccgtcacaagcaaagggcctcctcctc
agcgcaatcttccagagcaacaaccctgtcatcttcatggagcccaagatcctgtaccga
gcagcggttgagcacgttccaaatgaattctacacattatctcttaacaaagcggaagtg
gtcaaaccaggaaatgacgtgacggtcgtctcgtacggtcaaccaatgtatctctgctca
gaagccatcagagctattgaaaaggacatgggcgccagcgttgaactcattgatctccga
acaatatacccttgggaccgacaaactgtcctagacagcgtcaagaagaccggacgtgct
atcgtagtccacgagagtatgatcaattacggcgtcggtgctgaagttgctgctaccatc
caagatggcgccttcttgcgcctggaggctccagtgaagcgagtggctggctggagcacc
cacaccggccttacatttgagaaactcatcttacctgatgtcgcgagaatttatgatgct
atcaagcagacactggagtactga
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