Actinoplanes friuliensis: AFR_18665
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Entry
AFR_18665 CDS
T02892
Name
(GenBank) bifunctional uroporphyrinogen-III synthetase/response regulator domain protein
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
afs
Actinoplanes friuliensis
Pathway
afs00860
Porphyrin metabolism
afs01100
Metabolic pathways
afs01110
Biosynthesis of secondary metabolites
afs01120
Microbial metabolism in diverse environments
afs01240
Biosynthesis of cofactors
Module
afs_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
afs_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
afs_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
afs00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
AFR_18665
Enzymes [BR:
afs01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
AFR_18665
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
Trans_reg_C
Motif
Other DBs
NCBI-ProteinID:
AGZ42011
UniProt:
U5W244
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All DBs
Position
4088187..4089332
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AA seq
381 aa
AA seq
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MADSTGPVTPAGASAPDAPAGPLAGFTIAVTAERRRDELAALFQRRGAKVLVAPAITIVP
LGDDQALHAATEACVGLAPDIVIATTGIGFRGWLEAAEGWGMGDTLRAALSRARLIARGA
KPCGAIRAADLSEEWSAVTESSEEIQERLIAQGIAGRRIAVQLHGGPQAEFTAALRSAGA
AVVEIPVYRWTLPPDVSPVRRLVGQLAAGQVDAVTFTSAPAVQALLEIAGDNAADVLDSF
RTGTMAACVGPVTAASLVEQDVPVVTPHRSRLGALVKVVTDELPRRAPSLSVAGTTLEIR
GHAVLIDGRLQALAPAAMAILGALAARPGAVVSKDRLVASLPRGTDGHAVDVAVARLRTA
LGPAGHIETVIKRGYRLRVDE
NT seq
1146 nt
NT seq
+upstream
nt +downstream
nt
atggccgactcgaccgggccggtgacgcccgcgggcgcttccgcccccgacgcacccgcc
gggccgctggcgggtttcaccatcgcggtcaccgccgagcggcgccgcgacgagctcgcc
gcgctgttccagcgtcgcggcgcgaaggtcctggtcgcgcccgcgatcacgatcgtcccg
ctcggcgacgaccaggcgctgcacgccgcgaccgaggcctgcgtcggtctggcccccgac
atcgtcatcgccaccaccgggatcgggttccgtggctggctcgaggccgccgagggctgg
gggatgggcgacacgctgcgcgcggcactcagccgggcccggctcatcgcccgcggcgcg
aagccctgtggtgccatccgggcggccgacctgagcgaggagtggtcggcggtcaccgag
tcgtccgaggagatccaggagcggctgatcgcccagggcatcgcgggccgccgcatcgcg
gtccagctgcacggtggcccgcaggcggagttcaccgccgccctgcggtcggccggcgcc
gccgtcgtggagatcccggtctaccgctggacgcttccccccgacgtctccccggtacgc
cgcctcgtcggccagctcgcagccgggcaggtcgacgcggtcacgttcaccagcgcaccg
gccgtccaggcactgctggagatcgccggtgacaacgccgccgacgtgctcgacagcttc
cgcaccggcacgatggcggcctgcgtcggcccggtgaccgccgcgtccctggtcgagcag
gacgtcccggtggtgacaccgcaccggtcccggctcggcgccctggtcaaggtggtgacc
gacgagctgccccggcgcgccccgagcctgtcggtcgccggtacgacgctggagatccgt
ggccacgccgtgctcatcgacggccgcctccaggccctggccccggcggcgatggccatc
ctgggcgccctcgcggcccgcccgggtgcggtcgtctcgaaggaccgcctggtcgcgtcg
ctgccgcgcggcaccgacggtcacgccgtcgacgtcgccgtggcccgcctgcgcaccgcg
ctgggcccggcgggccacatcgagaccgtgatcaagcgcgggtaccggctgcgggtggac
gagtga
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