Antechinus flavipes (yellow-footed antechinus): 127553984
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Entry
127553984 CDS
T08818
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
afz
Antechinus flavipes (yellow-footed antechinus)
Pathway
afz00010
Glycolysis / Gluconeogenesis
afz00020
Citrate cycle (TCA cycle)
afz00620
Pyruvate metabolism
afz00785
Lipoic acid metabolism
afz01100
Metabolic pathways
afz01200
Carbon metabolism
afz01210
2-Oxocarboxylic acid metabolism
afz04066
HIF-1 signaling pathway
afz04922
Glucagon signaling pathway
afz05230
Central carbon metabolism in cancer
afz05415
Diabetic cardiomyopathy
Module
afz_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
afz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
127553984
00020 Citrate cycle (TCA cycle)
127553984
00620 Pyruvate metabolism
127553984
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
127553984
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
127553984
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
127553984
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
127553984
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
127553984
Enzymes [BR:
afz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
127553984
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
127553984
NCBI-ProteinID:
XP_051841113
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Position
3:complement(287387768..287411677)
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AA seq
395 aa
AA seq
DB search
MRKMLAVVSRVLTGASQKPGAASEVGRVLLASRNFANDATFDIKKCDIHRLEEGPPTTAV
LTREEGLKYYKIMQTVRRMELKADQLYKQKIIRGFCHLYDGQEACCMGLEAGINPTDHVI
TAYRAHGFTYTRGLPVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGA
GIALACKYNEKDEICLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVER
AAASTDYYKRGDFIPGIRVDGMDVLCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMS
DPGVSYRTREEIQEVRSKSDPIMLLKDRMVNNNLASIEELKEIDVEVRKEIEDAAQFATA
DPEPPLEELGYHIYSRDPPFEVRGANQWIKYKSVS
NT seq
1188 nt
NT seq
+upstream
nt +downstream
nt
atgcgaaaaatgctcgcagtcgtttcccgcgtgctgacgggcgcctcccagaaaccggga
gctgctagtgaggttggaagagtgctcctggcatcccgtaactttgcaaatgatgccacc
tttgatattaagaaatgtgacattcatcggcttgaggaaggccctcctaccacagcagtt
ctcactagggaggaaggactcaaatactataagatcatgcagactgtccgtcggatggaa
ttgaaagcagaccagctatataagcaaaagattatccgtgggttttgccacttgtatgat
ggtcaggaagcttgttgtatggggcttgaagctggtataaatcctacagatcatgttatt
acagcctatcgcgctcatggctttacatatactcgtggacttcctgttcgagaaattctg
gcagagcttacaggaagaagaggaggatgtgctaaaggaaagggaggatctatgcacatg
tacgccaagaacttctacggcggcaatggcattgttggagctcaggtacctctaggagct
ggtattgccctcgcctgtaagtacaatgaaaaagatgagatttgtttgactttgtatgga
gatggtgctgctaatcagggccaaatatttgaagcttacaatatggcagctttgtggaaa
ttgccttgtattttcatttgtgagaataaccgatatggaatgggaacttctgtagagaga
gcagcagccagcactgactattacaaaagaggagactttattccaggaataagggtagat
ggtatggatgttctgtgtgttcgtgaagcaacaaaatttgcagctgcctactgtagatca
ggaaagggccccatattgatggaactacagacatatcgttatcacggacatagcatgagt
gatcctggtgtcagttatcgcactcgggaagaaattcaggaagtgaggagtaagagtgat
cctatcatgcttctaaaagacagaatggtgaacaacaaccttgccagtattgaagaatta
aaggaaattgatgttgaagtaaggaaagagattgaggatgctgcccagtttgctacagcg
gatccagaaccacctttggaagaattaggctatcatatctactccagagatccacctttt
gaagttcgaggagcaaatcagtggatcaagtacaaatctgtcagctaa
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