Entry
Symbol
cefF
Name
(KEGG) deacetylcephalosporin C synthase (EC:1.14.11.26)
KO
Taxonomy
Lineage
Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces
Organism
Streptomyces clavuligerus
Taxonomy
SSDB
Ortholog Paralog GFIT
Motif
Motif
Other DBs
LinkDB
All DBs
AA seq
318 aa AA seq DB search
MADTPVPIFNLAALREGADQEKFRECVTGMGVFYLTGYGAGDKDHRLATDTAMDFFANGT
EAEKAAVTTDVPTMRRGYSALEAESTAQVTRTGSYTDYSMSFSMGISGNVFPSPEFERVW
TEYFDKLYAAAQETARLVLTASGGYDAEIVGSLDELLDADPVLRLRYFPEVPEHRSAEHE
PRRMAPHYDLSIITFIHQTPCANGFVSLQAEIGGELVSLPVVEDAVVVMCGAMAPLATQG
ALPAPRHHVRSPGAGMREGSDRTSSVFFLRPTTDFSFSVAKARSYGLAVDLDMETATFGD
WIGTNYVTMHAKNEPQAG
Reference
Authors
Kovacevic S, Miller JR
Title
Cloning and sequencing of the beta-lactam hydroxylase gene (cefF) from Streptomyces clavuligerus: gene duplication may have led to separate hydroxylase and expandase activities in the actinomycetes.
Journal
Reference
Authors
Baker BJ, Dotzlaf JE, Yeh WK
Title
Deacetoxycephalosporin C hydroxylase of Streptomyces clavuligerus. Purification, characterization, bifunctionality, and evolutionary implication.
Journal
J Biol Chem 266:5087-93 (1991)