KEGG   Addendum: AAF22288
Entry
AAF22288          CDS       T10000                                 
Symbol
PNAE
Name
(KEGG) polyneuridine-aldehyde esterase (EC:3.1.1.78)
  KO
K08233  polyneuridine-aldehyde esterase [EC:3.1.1.78]
Taxonomy
TAX:4060
  Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Rauvolfiinae; Rauvolfia
Organism
Rauvolfia serpentina
SSDB
Motif
Pfam: Abhydrolase_1 Abhydrolase_6 Hydrolase_4 Cutinase AIR2-like_ZnK4 Thioesterase Abhydrolase_8 PGAP1 Peptidase_S9
Other DBs
NCBI-ProteinID: AAF22288
GB: AF178576
UniProt: Q9SE93
Structure
LinkDB
AA seq 264 aa
MHSAANAKQQKHFVLVHGGCLGAWIWYKLKPLLESAGHKVTAVDLSAAGINPRRLDEIHT
FRDYSEPLMEVMASIPPDEKVVLLGHSFGGMSLGLAMETYPEKISVAVFMSAMMPDPNHS
LTYPFEKYNEKCPADMMLDSQFSTYGNPENPGMSMILGPQFMALKMFQNCSVEDLELAKM
LTRPGSLFFQDLAKAKKFSTERYGSVKRAYIFCNEDKSFPVEFQKWFVESVGADKVKEIK
EADHMGMLSQPREVCKCLLDISDS
Reference
PMID:10691977
  Authors
Dogru E, Warzecha H, Seibel F, Haebel S, Lottspeich F, Stockigt J
  Title
The gene encoding polyneuridine aldehyde esterase of monoterpenoid indole alkaloid biosynthesis in plants is an ortholog of the alpha/betahydrolase super family.
  Journal
Eur J Biochem 267:1397-406 (2000)
DOI:10.1046/j.1432-1327.2000.01136.x
Reference
PMID:12071952
  Authors
Mattern-Dogru E, Ma X, Hartmann J, Decker H, Stockigt J
  Title
Potential active-site residues in polyneuridine aldehyde esterase, a central enzyme of indole alkaloid biosynthesis, by modelling and site-directed mutagenesis.
  Journal
Eur J Biochem 269:2889-96 (2002)
DOI:10.1046/j.1432-1033.2002.02956.x

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