KEGG   Addendum: AAM77997
Entry
AAM77997          CDS       T10000                                 
Symbol
ncsB3
Name
(KEGG) 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase (EC:1.14.15.31)
  KO
K20420  2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31]
Taxonomy
TAX:1897
  Lineage
Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces
Organism
Streptomyces carzinostaticus
SSDB
Motif
Pfam: p450 DUF4449 TPR_9
Other DBs
NCBI-ProteinID: AAM77997
GB: AY117439
UniProt: Q84HB6
LinkDB
AA seq 410 aa
MCPYRLDPEGADTHGETARLREQGPIARVELQDGVLAWSVHDYAVAKQIMADERFSKNPR
KNWPAYINGEISNGWPLITWVAMDTMATQDGADHARLRKLLLKAFTERRVESMRPHIEKT
VKELLDNMAAKADDEIVDIKEMFHAELPTRLMCDLFGVPEERRAEVLAGGHKNIDTRISS
EAAEANLGQWQEAISDLVEYKRHHPGDDLTSALIEARDEGSRLSDSELIGTLHLLLGAGS
ETLVNALAHSSLALLVDADLRKKVTSGEIPWVNVWEETLRVESPVAHLPFRYATEDFEIG
GVKISKGDPLLVDFAGIGRDPAVHSDAPDEFDALRPDKTHLSFGHGVHYCLGARLAKHAW
MIGIPALFERFPDMELAVRRDELKGQGSFVVNGHASLPVHLKGRAAALAR
Reference
  Authors
Liu W, Nonaka K, Nie L, Zhang J, Christenson SD, Bae J, Van Lanen SG, Zazopoulos E, Farnet CM, Yang CF, Shen B
  Title
The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthases.
  Journal
Chem Biol 12:293-302 (2005)
DOI:10.1016/j.chembiol.2004.12.013
Reference
  Authors
Hang VT, Oh TJ, Yamaguchi T, Sohng JK
  Title
In vivo characterization of NcsB3 to establish the complete biosynthesis of the naphthoic acid moiety of the neocarzinostatin chromophore.
  Journal
FEMS Microbiol Lett 311:119-25 (2010)
DOI:10.1111/j.1574-6968.2010.02075.x

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