KEGG   Addendum: ALG05119
Entry
ALG05119          CDS       T10000                                 
Symbol
OMT3
Name
(KEGG) (-)-pluviatolide 4-O-methyltransferase (EC:2.1.1.323)
  KO
K21203  (-)-pluviatolide 4-O-methyltransferase [EC:2.1.1.323]
Taxonomy
TAX:93608
  Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; Ranunculales; Berberidaceae; Podophylloideae; Podophylleae; Sinopodophyllum
Organism
Sinopodophyllum hexandrum
Module
93608_M00902  Podophyllotoxin biosynthesis, coniferyl alcohol => podophyllotoxin
SSDB
Motif
Pfam: Methyltransf_2 Dimerisation Methyltransf_25 Methyltransf_12 Methyltransf_31 Methyltransf_PK Methyltransf_11 Methyltransf_16 Dimerisation2 MTS
Other DBs
NCBI-ProteinID: ALG05119
GB: KT390157
UniProt: A0A0N9HMN6
LinkDB
AA seq 372 aa
MEMAPTMDLEIRNGNGYGDSGEELLAAQAHIYNHIFNFISSMALKCAVELNIPEILHNHQ
PKAVTLSELVQALQIPQAKSACLYRLLRILVHSGFFAITKIQSEGDEEGYLPTLSSKLLL
KNHPMSMSPCLLGLVNPTMVAPMHFFSDWFKRSDDMTPFEATHGASLWKYFGETPHMAEI
FNEAMGCETRLAMSVVLKECKGKLEGISSLVDVGGGTGNVGRAIAEAFPNVKCTVLDLPQ
VVGNLKGSNNLEFVSGDMFQFIPPADVVFLKWILHDWNDEECIKILKRCKEAIPSKEEGG
KLIIIDMVVNDHNKGSYESTETQLFYDLTLMALLTGTERTETEWKKLFVAAGFTSYIISP
VLGLKSIIEVFP
Reference
PMID:26359402
  Authors
Lau W, Sattely ES
  Title
Six enzymes from mayapple that complete the biosynthetic pathway to the etoposide aglycone.
  Journal
Science 349:1224-8 (2015)
DOI:10.1126/science.aac7202

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