Actinomyces graevenitzii: M3I41_03525
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Entry
M3I41_03525 CDS
T08387
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
agh
Actinomyces graevenitzii
Pathway
agh00790
Folate biosynthesis
agh01100
Metabolic pathways
agh01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
agh00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
M3I41_03525
Enzymes [BR:
agh01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
M3I41_03525
6.3.2.17 tetrahydrofolate synthase
M3I41_03525
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Gene cluster
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
DUF4715
Motif
Other DBs
NCBI-ProteinID:
UQF80350
UniProt:
A0A9E7AH64
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Position
840929..842689
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AA seq
586 aa
AA seq
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MSEADSRGIDPELYEYLEAAQELDEISVAEAARREQSAQAAQAAAEEEDRQAIRALVEGS
LLAGSGDLDEVLLGLEGDVDADWEGQADEPSHSHQGEGQPGEADSHRQALARAAYEQGVR
ERLAQVEAQILARAPEHKVQPSLERVELALDYLGNPQKTFKAVHITGTNGKTSTSRMVER
LAAATGMRTGRFTSPHLHTIRERIALDGEPISAEGFIAAWEDVAPVIELVDAHSAKNGGP
RMSFFEVLTVMAYAVFADYPVDVAIVEVGMGGRWDATNVLDQATAVITPIGRDHERWLGS
TIGEIAYEKSGIIKPGATVIVAAQPEEAQAQILQAVADKRALLRQDVSGYVSFDARMDLE
AESLARENGGLAVASRQFAVGGQMLTLVTAAAVYEDVFLPLHGQYQAHNALLALAAAESL
FGGRALPAQIVENAFAQVTSPGRLEVVRTSPTVLVDAAHNPHGVSALRTALEESFPLKHL
VLVYAAMADKDVEGVLSELEPICEAVVCVPMDSPRAMELDDLVEIADDVFGSDRVRSATN
LVDAVDLAAQLAESSDDPLPSSGVLILGSVVLAAQARELFGLKASM
NT seq
1761 nt
NT seq
+upstream
nt +downstream
nt
atgagtgaagcagattcgcgcggcattgacccggaactatatgagtatttggaagccgcc
caggagcttgacgagatttctgtggctgaagctgcccgccgtgagcaatcagcccaggcc
gcccaggctgcagctgaggaggaggaccgccaagccatccgcgccctggtggagggttcc
ctgctagcgggcagtggcgacttagatgaggtgcttttaggccttgagggcgatgtcgac
gccgactgggaggggcaggcggacgagcccagtcacagccatcagggtgagggtcagcca
ggcgaagcggacagtcaccgccaagccctagcgcgcgccgcctatgagcagggggtgcgt
gagcgcctagcccaggtggaggcgcaaattttggctcgcgccccggagcacaaggtacag
ccctccttggagcgggtggagctggccttagactatttgggtaacccccaaaaaaccttt
aaagctgtacacatcaccggcactaacggtaaaacctccacctcgcgtatggtcgagcgg
ctagctgccgccaccggtatgcgcacgggccgtttcaccagtccccacctgcacactatc
cgtgagcgcatcgctctagatggggagcccatcagcgctgaaggatttattgctgcctgg
gaggatgtagccccggtaattgagttggttgacgcccacagcgctaaaaacggtgggccg
cgcatgagtttctttgaagtgctcaccgtgatggcttacgccgtgtttgctgactacccg
gtggatgtggccattgttgaggtgggtatgggtgggcgctgggacgccactaatgtgtta
gatcaggccactgccgtgattacccctattggccgcgaccatgagcgctggctgggctca
accattggggaaattgcttacgaaaagtcggggattatcaaacctggtgccacagttatt
gttgcggcccagcctgaggaagcccaagcccagattttgcaggcggtagctgataagcgc
gccctgctgcgccaggatgtaagtggttacgtcagctttgatgcccgcatggatctggaa
gctgaaagcttggcccgtgaaaatgggggactggcggtagctagccgacagtttgctgtg
ggcgggcagatgctcactttggtgacggccgcagctgtttatgaggacgtgtttttgcct
ttgcacggccagtatcaggcccacaatgcgttgctggctctggcggctgctgaaagcctg
tttggtggtagggctttgccggcgcagattgttgaaaatgcttttgctcaggtcactagc
cctggccgccttgaggtggtgcgcactagccccactgtgctggtggacgcggcccacaac
ccccacggcgtgagtgcattgcgcactgctctagaagagtctttccccttaaagcacctg
gtgctggtgtatgcggccatggctgataaggatgtggaaggggtgctttctgagctagag
ccgatctgtgaagctgtggtttgtgtgcctatggattcgcctcgggctatggagctagat
gatctggtggaaattgccgacgacgtctttggctctgatcgggtgcgtagcgccaccaac
ctggttgatgcggttgatttggcggcgcagctagctgaatcttctgacgatccgctgcct
tcaagtggggttttgatcttgggttcagtggttctagcggctcaggcgcgagaactattt
ggtcttaaagcaagtatgtaa
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